Interactions between biological macromolecules regulate various biological processes. Many molecular biology and biochemistry methods have been developed to detect this interaction, such as pull-down assay, co-immunoprecipitation (Co-IP), yeast two-hybrid analysis, surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC). However, fluorescence resonance energy transfer (FRET) technology has gained great popularity due to its ability to detect interactions with extremely high spatiotemporal resolution in physiological conditions in a non-invasive manner. As an expert in structural biology and protein research, Creative Biostructure is helping our customers with diverse basic and preclinical research services targeting coronavirus infections, including COVID-19. We offer FRET technology-based assay development and detection services for coronavirus research. SARS-CoV-2 FRET Assay https://www.creative-biostruct....ure.com/coronavirus/

 

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Fluorescence Resonance Energy Transfer (FRET) Assay for Coronavirus Research - Coronavirus

Creative Biostructure offers fluorescence resonance energy transfer (FRET) technology-based assay development and detection services for coronavirus research.

Creative Biostructure provides comprehensive services for the study on the interaction of biological macromolecules such as proteins involved in coronavirus research. Similar to surface plasmon resonance (SPR), bio-layer interferometry (BLI) is also a label-free binding technology that measures the binding kinetics of biomolecular interactions in real time. Coronavirus BLI Service https://www.creative-biostruct....ure.com/coronavirus/

 

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Bio-layer Interferometry (BLI) Technology for Coronavirus Research - Coronavirus

Creative Biostructure provides bio-layer interferometry (BLI) service for the study on the interaction of biological macromolecules such as proteins involved in coronavirus research.

Creative Biostructure is a leading service supplier in the field of structural biology with a team of specialists specializing in contract research services for basic and preclinical research related to coronavirus infection. Currently, we have established a surface plasmon resonance (SPR) method for protein interaction analysis associated with coronavirus research and support the development and optimization of SPR methods. Coronavirus Surface Plasmon Resonance https://www.creative-biostruct....ure.com/coronavirus/

 

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Surface Plasmon Resonance (SPR) for Coronavirus Research - Coronavirus

Creative Biostructure has established a surface plasmon resonance (SPR) method for protein interaction analysis associated with coronavirus research and support the development and optimization of SPR methods.

Creative Biostructure provides a complete contract crystallography service to support coronavirus infection-related research, including gene-to-structure pipelines at all stages from protein expression to structure determination. After successfully obtaining the high-quality diffraction pattern and diffraction data, the next challenge is to obtain the electron density map, which is the basis for reconstructing three-dimensional (3D) structural models and deducing detailed structural information. We can perform data processing and analysis based on high-resolution X-ray diffraction data to determine and refine the crystal structure. Coronavirus Phase Determination https://www.creative-biostruct....ure.com/coronavirus/

 

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Crystallography Data Analysis for Coronavirus Research - Coronavirus

Creative Biostructure can perform data processing and analysis based on high-resolution X-ray diffraction data to determine and refine the crystal structure.